S-1-propenylcysteine improves TNF-α-induced vascular endothelial barrier dysfunction by suppressing the GEF-H1/RhoA/Rac pathway

BACKGROUND: Vascular endothelial barrier function is maintained by cell-to-cell junctional proteins and contributes to vascular homeostasis. Various risk factors such as inflammation disrupt barrier function through down-regulation of these proteins and promote vascular diseases such as atherosclero...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Kunimura, Kayo, Miki, Satomi, Takashima, Miyuki, Suzuki, Jun-ichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883441/
https://ncbi.nlm.nih.gov/pubmed/33588881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00692-w
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