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Paracingulin Regulates the Activity of Rac1 and RhoA GTPases by Recruiting Tiam1 and GEF-H1 to Epithelial Junctions

Small GTPases control key cellular events, including formation of cell–cell junctions and gene expression, and are regulated by activating and inhibiting factors. Here, we characterize the junctional protein paracingulin as a novel regulator of the activity of two small GTPases, Rac1 and RhoA, throu...

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Autores principales: Guillemot, Laurent, Paschoud, Serge, Jond, Lionel, Foglia, Andrea, Citi, Sandra
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555940/
https://ncbi.nlm.nih.gov/pubmed/18653465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0558
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