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Paracingulin Regulates the Activity of Rac1 and RhoA GTPases by Recruiting Tiam1 and GEF-H1 to Epithelial Junctions

Small GTPases control key cellular events, including formation of cell–cell junctions and gene expression, and are regulated by activating and inhibiting factors. Here, we characterize the junctional protein paracingulin as a novel regulator of the activity of two small GTPases, Rac1 and RhoA, throu...

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Hlavní autoři: Guillemot, Laurent, Paschoud, Serge, Jond, Lionel, Foglia, Andrea, Citi, Sandra
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555940/
https://ncbi.nlm.nih.gov/pubmed/18653465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0558
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