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A Role for ZO-1 and PLEKHA7 in Recruiting Paracingulin to Tight and Adherens Junctions of Epithelial Cells

Paracingulin is a 160-kDa protein localized in the cytoplasmic region of epithelial tight and adherens junctions, where it regulates RhoA and Rac1 activities by interacting with guanine nucleotide exchange factors. Here, we investigate the molecular mechanisms that control the recruitment of paracin...

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Détails bibliographiques
Auteurs principaux: Pulimeno, Pamela, Paschoud, Serge, Citi, Sandra
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089516/
https://ncbi.nlm.nih.gov/pubmed/21454477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230862
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