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A Role for ZO-1 and PLEKHA7 in Recruiting Paracingulin to Tight and Adherens Junctions of Epithelial Cells

Paracingulin is a 160-kDa protein localized in the cytoplasmic region of epithelial tight and adherens junctions, where it regulates RhoA and Rac1 activities by interacting with guanine nucleotide exchange factors. Here, we investigate the molecular mechanisms that control the recruitment of paracin...

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Bibliographische Detailangaben
Hauptverfasser: Pulimeno, Pamela, Paschoud, Serge, Citi, Sandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089516/
https://ncbi.nlm.nih.gov/pubmed/21454477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230862
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