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ANKRD26 recruits PIDD1 to centriolar distal appendages to activate the PIDDosome following centrosome amplification
Centriole copy number is tightly maintained by the once‐per‐cycle duplication of these organelles. Centrioles constitute the core of centrosomes, which organize the microtubule cytoskeleton and form the poles of the mitotic spindle. Centrosome amplification is frequently observed in tumors, where it...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7883295/ https://ncbi.nlm.nih.gov/pubmed/33350495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105106 |
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