Vitamin D3 ameliorates nitrogen mustard‐induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3–SOD2–mtROS signaling pathway

Nitrogen mustard (NM) causes severe skin injury with an obvious inflammatory response, which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti‐inflammatory properties and is considered as a potential candidate for the treatment of NM‐induced dermal toxicity; however, t...

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Vydáno v:Clin Transl Med
Hlavní autoři: Dong, Xunhu, He, Ying, Ye, Feng, Zhao, Yuanpeng, Cheng, Jin, Xiao, Jingsong, Yu, Wenpei, Zhao, Jiqing, Sai, Yan, Dan, Guorong, Chen, Mingliang, Zou, Zhongmin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882108/
https://ncbi.nlm.nih.gov/pubmed/33634989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.312
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