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Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system.
The orexin (hypocretin) system plays a critical role in motivated drug-taking. Cocaine self-administration with the intermittent access (IntA) procedure produces a robust addiction-like state that is orexin-dependent. Here, we sought to determine the role of the orexin system in opioid addiction usi...
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| Veröffentlicht in: | Addict Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7882007/ https://ncbi.nlm.nih.gov/pubmed/32798290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12946 |
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