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Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system.

The orexin (hypocretin) system plays a critical role in motivated drug-taking. Cocaine self-administration with the intermittent access (IntA) procedure produces a robust addiction-like state that is orexin-dependent. Here, we sought to determine the role of the orexin system in opioid addiction usi...

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Xehetasun bibliografikoak
Argitaratua izan da:Addict Biol
Egile Nagusiak: Fragale, Jennifer E., James, Morgan H., Aston-Jones, Gary
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882007/
https://ncbi.nlm.nih.gov/pubmed/32798290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12946
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