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The role of orexin-1 receptor signaling in demand for the opioid fentanyl
The orexin system is a potential treatment target for drug addiction. Orexin-1 receptor (OxR1) antagonism reduces demand for cocaine and remifentanil, indicating that orexin-based therapies may reduce demand for many classes of abused drugs. However, pharmacokinetics vary greatly among opioids and i...
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| Veröffentlicht in: | Neuropsychopharmacology |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6785092/ https://ncbi.nlm.nih.gov/pubmed/31112988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0420-x |
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