The Dysregulated Galectin Network Activates NF-κB to Induce Disease Markers and Matrix Degeneration in 3D Pellet Cultures of Osteoarthritic Chondrocytes

This work aimed to study the dysregulated network of galectins in OA chondrocyte pellets, and to assess whether their recently discovered activity as molecular switches of functional biomarkers results in degradation of extracellular matrix in vitro. Scaffold-free 3D pellet cultures were established...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Calcif Tissue Int
Päätekijät: Pichler, K. M., Weinmann, D., Schmidt, S., Kubista, B., Lass, R., Martelanz, L., Alphonsus, J., Windhager, R., Gabius, H. -J., Toegel, S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2020
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881967/
https://ncbi.nlm.nih.gov/pubmed/33185768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-020-00774-4
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