Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1

Degeneration of the human intervertebral disc (IVD) is assumed to underlie severe clinical symptoms, in particular chronic back pain. Since adhesion/growth‐regulatory galectins are linked to arthritis/osteoarthritis pathogenesis by activating a pro‐degradative/‐inflammatory gene expression signature...

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Bibliografiske detaljer
Udgivet i:J Orthop Res
Main Authors: Elshamly, Mahmoud, Kinslechner, Katharina, Grohs, Josef G., Weinmann, Daniela, Walzer, Sonja M., Windhager, Reinhard, Gabius, Hans‐Joachim, Toegel, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771593/
https://ncbi.nlm.nih.gov/pubmed/31115931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24351
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