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Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1

Degeneration of the human intervertebral disc (IVD) is assumed to underlie severe clinical symptoms, in particular chronic back pain. Since adhesion/growth‐regulatory galectins are linked to arthritis/osteoarthritis pathogenesis by activating a pro‐degradative/‐inflammatory gene expression signature...

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Detalhes bibliográficos
Publicado no:J Orthop Res
Main Authors: Elshamly, Mahmoud, Kinslechner, Katharina, Grohs, Josef G., Weinmann, Daniela, Walzer, Sonja M., Windhager, Reinhard, Gabius, Hans‐Joachim, Toegel, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771593/
https://ncbi.nlm.nih.gov/pubmed/31115931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24351
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