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Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1

Degeneration of the human intervertebral disc (IVD) is assumed to underlie severe clinical symptoms, in particular chronic back pain. Since adhesion/growth‐regulatory galectins are linked to arthritis/osteoarthritis pathogenesis by activating a pro‐degradative/‐inflammatory gene expression signature...

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Bibliographische Detailangaben
Veröffentlicht in:J Orthop Res
Hauptverfasser: Elshamly, Mahmoud, Kinslechner, Katharina, Grohs, Josef G., Weinmann, Daniela, Walzer, Sonja M., Windhager, Reinhard, Gabius, Hans‐Joachim, Toegel, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771593/
https://ncbi.nlm.nih.gov/pubmed/31115931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24351
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