Glycophenotyping of osteoarthritic cartilage and chondrocytes by RT-qPCR, mass spectrometry, histochemistry with plant/human lectins and lectin localization with a glycoprotein

INTRODUCTION: This study aimed to characterize the glycophenotype of osteoarthritic cartilage and human chondrocytes. METHODS: Articular knee cartilage was obtained from nine osteoarthritis (OA) patients. mRNA levels for 27 glycosyltransferases were analyzed in OA chondrocytes using RT-qPCR. Additio...

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Autori principali: Toegel, Stefan, Bieder, Daniela, André, Sabine, Altmann, Friedrich, Walzer, Sonja M, Kaltner, Herbert, Hofstaetter, Jochen G, Windhager, Reinhard, Gabius, Hans-Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978707/
https://ncbi.nlm.nih.gov/pubmed/24289744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4330
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