Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function

Protein translation is essential for cell physiology, and dysregulation of this process has been linked to aging-related diseases such as type 2 diabetes. Reduced protein level of a requisite scaffolding protein of the initiation complex, eIF4G1, downstream of nutrients and insulin signaling is asso...

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Vydáno v:Diabetes
Hlavní autoři: Jo, Seokwon, Lockridge, Amber, Mohan, Ramkumar, Esch, Nicholas, Schlichting, Regina, Panigrahy, Neha, Essawy, Ahmad, Gustafson, Eric, Alejandro, Emilyn U.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2021
Témata:
Islet Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881850/
https://ncbi.nlm.nih.gov/pubmed/33115825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0057
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