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Islet O-GlcNAcylation is Required for Lipid Potentiation of Insulin Secretion through SERCA2
During early obesity, pancreatic β-cells compensate for increased metabolic demand through a transient phase of insulin hypersecretion that stabilizes blood glucose and forestalls diabetic progression. We found evidence that β-cell O-GlcNAcylation, a nutrient-responsive post-translational protein mo...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8114475/ https://ncbi.nlm.nih.gov/pubmed/32375037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107609 |
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