A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients

Studies have shown that tumor microenvironment (TME) might affect drug sensitivity and the classification of colorectal cancer (CRC). Using TME-specific gene signature to identify CRC subtypes with distinctive clinical relevance has not yet been tested. A total of 18 “bulk” RNA-seq datasets (total n...

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Vydáno v:NPJ Precis Oncol
Hlavní autoři: Zhu, Xiaoqiang, Tian, Xianglong, Ji, Linhua, Zhang, Xinyu, Cao, Yingying, Shen, Chaoqin, Hu, Ye, Wong, Jason W. H., Fang, Jing-Yuan, Hong, Jie, Chen, Haoyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881244/
https://ncbi.nlm.nih.gov/pubmed/33580207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00142-x
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