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A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients

Studies have shown that tumor microenvironment (TME) might affect drug sensitivity and the classification of colorectal cancer (CRC). Using TME-specific gene signature to identify CRC subtypes with distinctive clinical relevance has not yet been tested. A total of 18 “bulk” RNA-seq datasets (total n...

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Detalhes bibliográficos
Publicado no:NPJ Precis Oncol
Main Authors: Zhu, Xiaoqiang, Tian, Xianglong, Ji, Linhua, Zhang, Xinyu, Cao, Yingying, Shen, Chaoqin, Hu, Ye, Wong, Jason W. H., Fang, Jing-Yuan, Hong, Jie, Chen, Haoyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881244/
https://ncbi.nlm.nih.gov/pubmed/33580207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00142-x
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