m6A-dependent glycolysis enhances colorectal cancer progression

Abstract Background Epigenetic alterations are involved in various aspects of colorectal carcinogenesis. N 6-methyladenosine (m6A) modifications of RNAs are emerging as a new layer of epigenetic regulation. As the most abundant chemical modification of eukaryotic mRNA, m6A is essential for the regul...

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Hlavní autoři: Chaoqin Shen, Baoqin Xuan, Tingting Yan, Yanru Ma, Pingping Xu, Xianglong Tian, Xinyu Zhang, Yingying Cao, Dan Ma, Xiaoqiang Zhu, Youwei Zhang, Jing-Yuan Fang, Haoyan Chen, Jie Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2020-04-01
Edice:Molecular Cancer
Témata:
m6A modification
METTL3
Glycolysis
Colorectal cancer
HK2
GLUT1
On-line přístup:http://link.springer.com/article/10.1186/s12943-020-01190-w
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