Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology

Tauopathies display a spectrum of phenotypes from cognitive to affective behavioral impairments; however, mechanisms promoting tau pathology and how tau elicits behavioral impairment remain unclear. We report a unique interaction between polyamine metabolism, behavioral impairment, and tau fate. Pol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Sandusky-Beltran, Leslie A., Kovalenko, Andrii, Placides, Devon S., Ratnasamy, Kevin, Ma, Chao, Hunt, Jerry B., Liang, Huimin, Calahatian, John Ivan T., Michalski, Camilla, Fahnestock, Margaret, Blair, Laura J., Darling, April L., Baker, Jeremy D., Fontaine, Sarah N., Dickey, Chad A., Gamsby, Joshua J., Nash, Kevin R., Abner, Erin, Selenica, Maj-Linda B., Lee, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880423/
https://ncbi.nlm.nih.gov/pubmed/33586680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126299
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados