MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT

Prostate cancer (PCa) is the second leading cause of cancer death in American men. Androgen receptor (AR) signaling is essential for PCa cell growth/survival and remains a key therapeutic target for lethal castration-resistant PCa (CRPC). GATA2 is a pioneer transcription factor crucial for inducing...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Shen, Tao, Wang, Wei, Zhou, Wolong, Coleman, Ilsa, Cai, Qinbo, Dong, Bingning, Ittmann, Michael M., Creighton, Chad J., Bian, Yingnan, Meng, Yanling, Rowley, David R., Nelson, Peter S., Moore, David D., Yang, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880415/
https://ncbi.nlm.nih.gov/pubmed/33586682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135465
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