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MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT

Prostate cancer (PCa) is the second leading cause of cancer death in American men. Androgen receptor (AR) signaling is essential for PCa cell growth/survival and remains a key therapeutic target for lethal castration-resistant PCa (CRPC). GATA2 is a pioneer transcription factor crucial for inducing...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Shen, Tao, Wang, Wei, Zhou, Wolong, Coleman, Ilsa, Cai, Qinbo, Dong, Bingning, Ittmann, Michael M., Creighton, Chad J., Bian, Yingnan, Meng, Yanling, Rowley, David R., Nelson, Peter S., Moore, David D., Yang, Feng
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880415/
https://ncbi.nlm.nih.gov/pubmed/33586682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135465
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