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Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine
The Hippo pathway is an evolutionarily conserved signalling pathway with key roles in organ development, epithelial homeostasis, tissue regeneration, wound healing and immune modulation. Many of these roles are mediated by the transcriptional effectors YAP and TAZ, which direct gene expression via c...
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| Publicado en: | Nat Rev Drug Discov |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7880238/ https://ncbi.nlm.nih.gov/pubmed/32555376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-0070-z |
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