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The Hippo signaling pathway in stem cell biology and cancer

The Hippo signaling pathway, consisting of a highly conserved kinase cascade (MST and Lats) and downstream transcription coactivators (YAP and TAZ), plays a key role in tissue homeostasis and organ size control by regulating tissue-specific stem cells. Moreover, this pathway plays a prominent role i...

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Detalhes bibliográficos
Main Authors: Mo, Jung-Soon, Park, Hyun Woo, Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197875/
https://ncbi.nlm.nih.gov/pubmed/24825474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438638
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