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The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
The Hippo signaling pathway is an emerging growth control and tumor suppressor pathway that regulates cell proliferation and stem cell functions. Defects in Hippo signaling and hyperactivation of its downstream effectors YAP and TAZ contribute to the development of cancer, suggesting that pharmacolo...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167640/ https://ncbi.nlm.nih.gov/pubmed/24336504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4161 |
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