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Do haematopoietic stem cells age?
Genetic defects that accumulate in haematopoietic stem cells (HSCs) are thought to be responsible for age-related changes in haematopoiesis that include a decline in lymphopoiesis and skewing towards the myeloid lineage. This HSC-centric view is based largely on studies showing that HSCs from aged m...
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| Publicado en: | Nat Rev Immunol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7879798/ https://ncbi.nlm.nih.gov/pubmed/31740804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0236-2 |
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