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Do haematopoietic stem cells age?
Genetic defects that accumulate in haematopoietic stem cells (HSCs) are thought to be responsible for age-related changes in haematopoiesis that include a decline in lymphopoiesis and skewing towards the myeloid lineage. This HSC-centric view is based largely on studies showing that HSCs from aged m...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Rev Immunol |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7879798/ https://ncbi.nlm.nih.gov/pubmed/31740804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0236-2 |
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