Modified Riceberry rice extract suppresses melanogenesis-associated cell differentiation through tyrosinase-mediated MITF downregulation on B16 cells and in vivo zebrafish embryos

BACKGROUND AND PURPOSE: Excessive melanin production caused by overactive tyrosinase (TYR) enzyme results in several dermatological problems. The TYR inhibitor, derived from metabolite changes during fermentation, has been well recognized for pigmentation control. EXPERIMENTAL APPROACH: This study i...

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Publicado en:Res Pharm Sci
Autores principales: Rodboon, Teerapat, Sirilun, Sasithorn, Okada, Seiji, Kariya, Ryusho, Chontananarth, Thapana, Suwannalert, Prasit
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer - Medknow 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879784/
https://ncbi.nlm.nih.gov/pubmed/33628291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.297852
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