Inhibition of melanogenesis by jineol from Scolopendra subspinipes mutilans via MAP-Kinase mediated MITF downregulation and the proteasomal degradation of tyrosinase

In this study, the authors investigated the anti-melanogenic effects of 3,8-dihydroxyquinoline (jineol) isolated from Scolopendra subspinipes mutilans, the mechanisms responsible for its inhibition of melanogenesis in melan-a cells, and its antioxidant efficacy. Mushroom tyrosinase activities and me...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alam, Md Badrul, Bajpai, Vivek K., Lee, JungIn, Zhao, Peijun, Byeon, Jung-Hee, Ra, Jeong-Sic, Majumder, Rajib, Lee, Jong Sung, Yoon, Jung-In, Rather, Irfan A., Park, Yong-Ha, Kim, Kangmin, Na, MinKyun, Lee, Sang-Han
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385534/
https://ncbi.nlm.nih.gov/pubmed/28393917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45858
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