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Knockdown of the DJ-1 (PARK7) gene sensitizes pancreatic cancer to erlotinib inhibition

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib, in combination with gemcitabine, has been shown to be a promising therapy in the treatment of pancreatic cancer. Our previous study showed that DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activat...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: He, Xiangyi, Sun, Yunwei, Fan, Rong, Sun, Jing, Zou, Douwu, Yuan, Yaozong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878983/
https://ncbi.nlm.nih.gov/pubmed/33614917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.01.013
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