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Knockdown of the DJ-1 (PARK7) gene sensitizes pancreatic cancer to erlotinib inhibition
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib, in combination with gemcitabine, has been shown to be a promising therapy in the treatment of pancreatic cancer. Our previous study showed that DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activat...
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| Publicat a: | Mol Ther Oncolytics |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Gene & Cell Therapy
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7878983/ https://ncbi.nlm.nih.gov/pubmed/33614917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.01.013 |
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