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DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses
In cancer, DJ-1/PARK7 acts as an oncogene that drives Akt-mediated cell survival. Although amplification of DJ-1 has been described in several types of tumors, the mechanistic basis of DJ-1's oncogenic effect remains incompletely understood. A tumor's ability to adapt to hypoxia is absolut...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626605/ https://ncbi.nlm.nih.gov/pubmed/19144925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812745106 |
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