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Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2
An efficient treatment against a COVID-19 disease, caused by the novel coronavirus SARS-CoV-2 (CoV2), remains a challenge. The papain-like protease (PL(pro)) from the human coronavirus is a protease that plays a critical role in virus replication. Moreover, CoV2 uses this enzyme to modulate the host...
Gorde:
| Argitaratua izan da: | Sci Rep |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7878891/ https://ncbi.nlm.nih.gov/pubmed/33574416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83229-6 |
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