CK2 Inhibits TIMELESS Nuclear Export and Modulates CLOCK Transcriptional Activity to Regulate Circadian Rhythms

Circadian clocks orchestrate daily rhythms in organismal physiology and behavior to promote optimal performance and fitness. In Drosophila, key pacemaker proteins PERIOD (PER) and TIMELESS (TIM) are progressively phosphorylated to perform phase-specific functions. Whereas PER phosphorylation has bee...

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I publikationen:Curr Biol
Huvudupphovsmän: Cai, Yao D., Xue, Yongbo, Truong, Cindy C., Del Carmen-Li, Jose, Ochoa, Christopher, Vanselow, Jens T., Murphy, Katherine A., Li, Ying H., Liu, Xianhui, Kunimoto, Ben L., Zheng, Haiyan, Zhao, Caifeng, Zhang, Yong, Schlosser, Andreas, Chiu, Joanna C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878342/
https://ncbi.nlm.nih.gov/pubmed/33217322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.10.061
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