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A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock

Post-translational processes are essential for the generation and dynamics of mammalian circadian rhythms. In particular, phosphorylation of the key circadian protein PER2 precisely controls the period and phase of circadian oscillations. However, the mechanisms underlying that control are poorly un...

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Bibliographic Details
Main Authors: Maier, Bert, Wendt, Sabrina, Vanselow, Jens T., Wallach, Thomas, Reischl, Silke, Oehmke, Stefanie, Schlosser, Andreas, Kramer, Achim
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661607/
https://ncbi.nlm.nih.gov/pubmed/19299560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.512209
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