Gut Helicobacter presentation by multiple dendritic cell subsets enables context-specific regulatory T cell generation

Generation of tolerogenic peripheral regulatory T (pTreg) cells is commonly thought to involve CD103(+) gut dendritic cells (DCs), yet their role in commensal-reactive pTreg development is unclear. Using two Helicobacter-specific T cell receptor (TCR) transgenic mouse lines, we found that both CD103...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Russler-Germain, Emilie V, Yi, Jaeu, Young, Shannon, Nutsch, Katherine, Wong, Harikesh S, Ai, Teresa L, Chai, Jiani N, Durai, Vivek, Kaplan, Daniel H, Germain, Ronald N, Murphy, Kenneth M, Hsieh, Chyi-Song
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
Soggetti:
Immunology and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877908/
https://ncbi.nlm.nih.gov/pubmed/33533717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54792
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi