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Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian cycle

The circadian clock drives extensive temporal gene expression programs controlling daily changes in behavior and physiology. In mouse liver, transcription factors dynamics, chromatin modifications, and RNA Polymerase II (PolII) activity oscillate throughout the 24-hour (24h) day, regulating the rhyt...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Mermet, Jérôme, Yeung, Jake, Naef, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877755/
https://ncbi.nlm.nih.gov/pubmed/33524027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009350
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