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Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian cycle

The circadian clock drives extensive temporal gene expression programs controlling daily changes in behavior and physiology. In mouse liver, transcription factors dynamics, chromatin modifications, and RNA Polymerase II (PolII) activity oscillate throughout the 24-hour (24h) day, regulating the rhyt...

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Publicado en:PLoS Genet
Autores principales: Mermet, Jérôme, Yeung, Jake, Naef, Felix
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877755/
https://ncbi.nlm.nih.gov/pubmed/33524027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009350
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