JNK1 ablation improves pancreatic β‐cell mass and function in db/db diabetic mice without affecting insulin sensitivity and adipose tissue inflammation

The cJun N‐terminal Kinases (JNK) emerged as a major link between obesity and insulin resistance, but their role in the loss of pancreatic β‐cell mass and function driving the progression from insulin resistance to type‐2 diabetes and in the complications of diabetes was not investigated to the same...

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Sparad:
Bibliografiska uppgifter
I publikationen:FASEB Bioadv
Huvudupphovsmän: Mazzoli, Arianna, Sardi, Claudia, Breasson, Ludovic, Theilig, Franziska, Becattini, Barbara, Solinas, Giovanni
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876705/
https://ncbi.nlm.nih.gov/pubmed/33615154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2020-00081
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