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Genetic deletion of the 67‐kDa isoform of glutamate decarboxylase alters conditioned fear behavior in rats

The GABAergic system is thought to play an important role in the control of cognition and emotion, such as fear, and is related to the pathophysiology of psychiatric disorders. For example, the expression of the 67‐kDa isoform of glutamate decarboxylase (GAD67), a GABA‐producing enzyme, is downregul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:FEBS Open Bio
Hauptverfasser: Fujihara, Kazuyuki, Sato, Takumi, Miyasaka, Yoshiki, Mashimo, Tomoji, Yanagawa, Yuchio
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876494/
https://ncbi.nlm.nih.gov/pubmed/33325157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13065
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