The Role of the U5 snRNP in Genetic Disorders and Cancer

Pre-mRNA splicing is performed by the spliceosome, a dynamic macromolecular complex consisting of five small uridine-rich ribonucleoprotein complexes (the U1, U2, U4, U5, and U6 snRNPs) and numerous auxiliary splicing factors. A plethora of human disorders are caused by genetic variants affecting th...

Full description

Saved in:
Bibliographic Details
Published in:Front Genet
Main Authors: Wood, Katherine A., Eadsforth, Megan A., Newman, William G., O’Keefe, Raymond T.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876476/
https://ncbi.nlm.nih.gov/pubmed/33584830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.636620
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items