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The Role of the U5 snRNP in Genetic Disorders and Cancer
Pre-mRNA splicing is performed by the spliceosome, a dynamic macromolecular complex consisting of five small uridine-rich ribonucleoprotein complexes (the U1, U2, U4, U5, and U6 snRNPs) and numerous auxiliary splicing factors. A plethora of human disorders are caused by genetic variants affecting th...
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| Publicado en: | Front Genet |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7876476/ https://ncbi.nlm.nih.gov/pubmed/33584830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.636620 |
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