Trace Elements Status and Metallothioneins DNA Methylation Influence Human Hepatocellular Carcinoma Survival Rate

BACKGROUND: Mechanisms underlying hepatocellular carcinoma (HCC) development are largely unknown. The role of trace elements and proteins regulating metal ions homeostasis, i.e. metallothioneins (MTs), recently gained an increased interest. Object of the study was to investigate the role of promoter...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Udali, Silvia, De Santis, Domenica, Mazzi, Filippo, Moruzzi, Sara, Ruzzenente, Andrea, Castagna, Annalisa, Pattini, Patrizia, Beschin, Greta, Franceschi, Antonia, Guglielmi, Alfredo, Martinelli, Nicola, Pizzolo, Francesca, Ambrosani, Francesca, Olivieri, Oliviero, Choi, Sang-Woon, Friso, Simonetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876470/
https://ncbi.nlm.nih.gov/pubmed/33585212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.596040
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