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A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

The global impact of somatic structural variants (SSVs) on gene expression in pediatric brain tumors has not been thoroughly characterised. Here, using whole-genome and RNA sequencing from 854 tumors of more than 30 different types from the Children’s Brain Tumor Tissue Consortium, we report the alt...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Zhang, Yiqun, Chen, Fengju, Donehower, Lawrence A., Scheurer, Michael E., Creighton, Chad J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876141/
https://ncbi.nlm.nih.gov/pubmed/33568653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21081-y
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