A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

The global impact of somatic structural variants (SSVs) on gene expression in pediatric brain tumors has not been thoroughly characterised. Here, using whole-genome and RNA sequencing from 854 tumors of more than 30 different types from the Children’s Brain Tumor Tissue Consortium, we report the alt...

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Vydáno v:Nat Commun
Hlavní autoři: Zhang, Yiqun, Chen, Fengju, Donehower, Lawrence A., Scheurer, Michael E., Creighton, Chad J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876141/
https://ncbi.nlm.nih.gov/pubmed/33568653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21081-y
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