Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington’s disease

Brain-derived neurotrophic factor (BDNF) is implicated in the survival of striatal neurons. BDNF function is reduced in Huntington’s disease (HD), possibly because mutant huntingtin impairs its cortico-striatal transport, contributing to striatal neurodegeneration. The BDNF trophic pathway is a ther...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ou, Zhen-Yi Andy, Byrne, Lauren M., Rodrigues, Filipe B., Tortelli, Rosanna, Johnson, Eileanoir B., Foiani, Martha S., Arridge, Marzena, De Vita, Enrico, Scahill, Rachael I., Heslegrave, Amanda, Zetterberg, Henrik, Wild, Edward J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876124/
https://ncbi.nlm.nih.gov/pubmed/33568689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83000-x
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