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Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntington’s disease

Molecular markers derived from cerebrospinal fluid (CSF) represent an accessible means of exploring the pathobiology of Huntington’s disease (HD) in vivo. The endo-lysosomal/autophagy system is dysfunctional in HD, potentially contributing to disease pathogenesis and representing a potential target...

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Publicat a:PLoS One
Autors principals: Lowe, Alexander J., Sjödin, Simon, Rodrigues, Filipe B., Byrne, Lauren M., Blennow, Kaj, Tortelli, Rosanna, Zetterberg, Henrik, Wild, Edward J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430717/
https://ncbi.nlm.nih.gov/pubmed/32804976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233820
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