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Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease

Huntington's disease (HD) is a hereditary neurodegenerative condition with no therapeutic intervention known to alter disease progression, but several trials are ongoing and biomarkers of disease progression are needed. Tau is an axonal protein, often altered in neurodegeneration, and recent st...

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Détails bibliographiques
Publié dans:J Neurochem
Auteurs principaux: Rodrigues, Filipe Brogueira, Byrne, Lauren, McColgan, Peter, Robertson, Nicola, Tabrizi, Sarah J., Leavitt, Blair R., Zetterberg, Henrik, Wild, Edward J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053298/
https://ncbi.nlm.nih.gov/pubmed/27344050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13719
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