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Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells

Xanthatin (Xa) is a bicyclic sesquiterpene lactone identified from the plant Xanthium L. with impressive antitumor activity, but the role of Xa in non‐small cell lung cancer (NSCLC) is not known. Here we found that Xa inhibits proliferation, migration, invasion and induces apoptosis in NSCLC cells....

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Publicat a:J Cell Mol Med
Autors principals: Zhang, Jian, Yang, Sheng, Guan, Hongmei, Zhou, Jueyu, Gao, Yuan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875932/
https://ncbi.nlm.nih.gov/pubmed/33439503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16271
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