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Regulatory genomic circuitry of human disease loci by integrative epigenomics
Annotating the molecular basis of human disease remains an unsolved challenge, as 93% of disease loci are non-coding and gene-regulatory annotations are highly incomplete(1–3). Here we present EpiMap, a compendium comprising 10,000 epigenomic maps across 800 samples, which we used to define chromati...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875769/ https://ncbi.nlm.nih.gov/pubmed/33536621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03145-z |
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