Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

Genetic variants identified by genome-wide association studies explain only a modest proportion of heritability, suggesting that meaningful associations lie 'hidden' below current thresholds. Here, we integrate information from association studies with epigenomic maps to demonstrate that e...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:eLife
Autors principals: Wang, Xinchen, Tucker, Nathan R, Rizki, Gizem, Mills, Robert, Krijger, Peter HL, de Wit, Elzo, Subramanian, Vidya, Bartell, Eric, Nguyen, Xinh-Xinh, Ye, Jiangchuan, Leyton-Mange, Jordan, Dolmatova, Elena V, van der Harst, Pim, de Laat, Wouter, Ellinor, Patrick T, Newton-Cheh, Christopher, Milan, David J, Kellis, Manolis, Boyer, Laurie A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Genomics and Evolutionary Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862755/
https://ncbi.nlm.nih.gov/pubmed/27162171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10557
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars